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What is Botox resistance And how can you avoid it

What is Botox resistance? And how can you avoid it?

Botox is often hailed as the go-to solution for wrinkles, almost like a magic wand in cosmetic treatments. When in the hands of a skilled cosmetic doctor, success in rejuvenating your skin/appearance is virtually guaranteed. But what happens when Botox doesn’t do the trick? If you have faced this and found yourself searching the internet for answers, you might have stumbled upon the term “Botox resistance.” Questions like “Am I immune to Botox?” and “Is there a solution?” are probably swirling in your mind. The good news? Immunity to Botox is rare, and yes, there are effective strategies to tackle this issue, and we can assist you.

Considering the complexity and the buzz around this topic, it is essential to demystify it with expert insights. Let’s explore why Botox might not work as expected and explore the solutions our cosmetic doctor, Dr Kieren Bong, can offer to enhance your experience.

What exactly is BOTOX resistance?

Imagine BOTOX resistance as a rare scenario where a patient either develops antibodies against botulinum toxin or metabolises the BOTOX drug unusually fast. In such cases, the effectiveness of BOTOX injections diminishes, leading to disappointing outcomes, fleeting effects, or sometimes no noticeable change. However, actual BOTOX resistance is relatively uncommon. Clinical trials by the manufacturer revealed that a mere 1.5% of patients developed any ‘neutralising antibodies’ to BOTOX. Some experts even suggest that genuine BOTOX resistance might be as low as 1 in 10,000 patients.

Essence Medical Cosmetic Clinic is one of Scotland’s most reputable and respected Botox clinics, and as such, we often see patients who have yet to have the best results elsewhere. Our extensive experience has found that most instances where BOTOX seems less effective don’t actually stem from real BOTOX resistance. Instead, they are usually due to one of these factors:

1) Insufficient Waiting Time for BOTOX’s Full Effect

BOTOX is known for its prompt action, yet it is not instantaneous. Many patients start seeing a reduction in wrinkles within 48 hours, but achieving the complete effect can take up to 10 days. In our experience, the onset of results may sometimes even begin after a week. Patience is key here. If it has been over two weeks and the anticipated results are still elusive, it is time to talk to your provider.

2) Transitioning to a New Provider

Opting for a conservative approach with BOTOX is much safer than overtreating—after all, there is no antidote for excessive BOTOX; one can only wait it out. Therefore, reputable and experienced injectors often err on the side of caution with new patients. If you have recently switched to a new provider with a solid reputation, they might be taking this cautious route to precisely tailor the proper dosage for you. If results aren’t noticeable after a few weeks, a simple solution could be a minor adjustment or touch-up.

3) Adjusting to Ageing: Time to Revise Your Injectable Treatment Plan

For those who have made BOTOX a regular part of their beauty regimen, it is easy to overlook that ageing still progresses, albeit ‘behind the scenes’. If your usual BOTOX dosage isn’t delivering the results it used to, it might be a sign that your skin has undergone natural changes. This could include a loss of collagen and elastin or a reduction in facial fat volume. Such changes can transform lines that were initially only noticeable during facial expressions into more pronounced wrinkles. In these instances, there may be more effective approaches than simply increasing the dosage of BOTOX. A more holistic treatment plan, combining BOTOX with injectable fillers to restore skin volume, can be a more fitting strategy. This approach helps preserve a youthful appearance while maintaining the natural dynamics of your facial expressions.

4) Injector Errors: Dosage and Injection Site Mistakes

Mastery of facial anatomy, a keen ability to understand a patient’s aspirations, and the skill to inject the correct BOTOX dosage according to skin quality and precise tissue depth are critical for anyone administering cosmetic injections. This is precisely why our cosmetic doctor takes it upon himself to perform injections for all his patients personally. Less experienced practitioners may inadvertently err in dosage or inject at an incorrect location on the facial muscle. Such errors can lead to subpar results or even complications. To reduce the risk, it is advisable to choose a clinician with a solid track record of successful BOTOX treatments, ideally a doctor well-versed in cosmetic medicine.

While the lure of a more affordable Botox treatment by a non-medically trained injector might be tempting, it is essential to remember that doctors typically have a deeper understanding of three-dimensional facial anatomy and skin depth. This expertise often stems from their comprehensive training, which includes studying human anatomy through cadaver dissection during medical school. Opting for a medically trained professional ensures higher precision and safety in your Botox treatment.

5) Finding the Right Fit: Exploring Alternative Brands of Botulinum Toxin

Individual brand differences play a significant role in the effectiveness of your Botox treatments. Similar to how some individuals find paracetamol more effective for headaches while others prefer Ibuprofen, the same principle applies to Botulinum toxin brands. Some patients may respond better to a brand other than BOTOX despite the similarities between the products. At Essence Medical Cosmetic Clinic in Glasgow, we understand this variability. That’s why we stock a variety of commercial Botulinum toxin brands. Our cosmetic doctor is equipped to assist you in determining whether an alternative brand might yield better results than BOTOX. It is all about finding the perfect match for your unique needs and ensuring you receive the most effective treatment tailored to you.

6) Navigating the Risks of Over-Diluted or Counterfeit BOTOX

Regrettably, the cosmetic industry is not immune to unethical practices. Some injectors offer discounted “Botox” treatments, which may either be excessively diluted to increase profits or, worse, not genuine BOTOX at all. This issue is more prevalent in beauty salons and non-medical or semi-medical establishments, as only licensed clinicians can procure authentic BOTOX. To safeguard yourself from the potential hazards of counterfeit or poorly administered BOTOX, it is crucial to trust only skilled and qualified medical professionals at established medical clinics. Remember, if the price seems unbelievably low, it is likely too good to be true.

Botox is classified as a prescription medication in the United Kingdom, making a face-to-face consultation with a licensed prescriber mandatory before undergoing the procedure. Suppose a non-medical practitioner carries out your treatment without a prior consultation with a licensed prescriber. In that case, there is a high probability that the product used is either counterfeit or has yet to be subjected to rigorous and approved manufacturing standards. Always ensure the legitimacy and safety of your Botox treatment by choosing the right medical professionals and settings.

Botox in the right hands

Taking Steps When BOTOX Doesn’t Deliver Desired Results

Your first move should be to reconnect with your treatment provider. A credible injector will always be concerned if you are not completely happy with the outcome of your treatment and will strive to ensure your satisfaction. However, if you have reservations about returning to the same practitioner, feel free to seek a second opinion or consider switching to a well-respected doctor. It is a good idea to obtain a copy of your case notes from your previous provider and bring them to your new one. These notes are invaluable as they document your past treatments, including the date of your last BOTOX session, the injection sites, and the dosages used. This information is crucial for your new provider to create a treatment plan that is both safe and effective.

If you are searching for an experienced and trustworthy BOTOX provider in Glasgow, we invite you to book a consultation with our cosmetic doctor, Dr Kieren Bong, at Essence Medical Cosmetic Clinic. During your visit, we will take the time to thoroughly discuss your objectives and concerns and answer any queries you might have to tailor a treatment that best suits your individual needs. To arrange an appointment, contact us.


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