DIScover THE POWER OF PoLYNUCLEOTIDES

Imagine the synergistic effects of polynucleotides and Botox combined in a single syringe—a blend made in heaven. When this fusion of two magical compounds is administered with a one-of-a-kind injection device to a precise depth in the skin under your eyes, the results are brighter, smoother, and tighter under-eyes.

The power of Dr Bong’s Polynucleotide EyeBright formula comes from using our industry’s highest polynucleotide concentration within a syringe, coupled with a fine dose of Botox. This potent concoction is then loaded onto our one-of-a-kind skin injection device, allowing precise injection depth calibration. Polynucleotides work best within the dermis of our skin, and this is where Dr Bong’s powerful concoction is injected with the most exacting accuracy.

Powerful formulation plus exacting injection accuracy equals maximum results.

• Reduce dark circles
• Smooth fine lines and wrinkles beneath the eyes
• Tighten and firm skin beneath the eyes
• Enhance skin hydration and circulation beneath the eyes

Not all polynucleotide brands are created equal, as discussed above. Our high-dose Polynucleotide EyeBright treatment is particularly efficacious, enhancing collagen and elastin production by stimulating fibroblast cells. It also promotes tissue regeneration and restores skin tone and elasticity. Additionally, this treatment offers antioxidant and hydrating benefits, complementing its bio-remodelling effects. The result is skin that not only looks but feels markedly healthier, reflecting the superior quality of our chosen formulation.

In Europe, the landscape of polynucleotide brands varies, and so too does the concentration of polynucleotides in each millilitre (ml) of their offerings. To illustrate, Lumi-Eyes, widely accessible cheaply online and often used by beauticians, contains a modest 2mg per ml of polynucleotides. In contrast, Plinest Eye boasts a concentration of 7.5mg per ml, while PhilArt Eye by Croma leads with an impressive 15mg per ml. Understandably, the cost of these products escalates with the concentration of active ingredients.

Safety is a paramount concern with these treatments. Both Plinest and PhilArt are underpinned by an extensive array of clinical studies demonstrating their safety, boasting a solid foundation of evidence. Lumi-Eyes, however, relies primarily on manufacturer claims for its safety assertions.

At Essence Medical Cosmetic Clinic, our Polynucleotide EyeBright treatment utilises a polynucleotide sourced exclusively from one of Europe’s leading pharmaceutical firms, noted for its expansive and forward-thinking range of aesthetic products. Their diverse portfolio not only encompasses polynucleotides but also includes botulinum toxin, hyaluronic acid fillers, PDO threads, biostimulators, and their own skincare brand, providing a comprehensive approach to beauty and wellness.

The polynucleotide used in our EyeBright treatment boasts an exceptionally high concentration of 20mg per ml, designed to deliver maximum benefits with fewer sessions. This high potency formulation ensures that our patients receive the most effective results, efficiently and effectively.

This is an exclusive formula created by Dr Kieren Bong, one of Europe’s most respected cosmetic doctors. With over 15 years of full-time experience in aesthetic medicine and unparalleled expertise in the use of injectable bio-stimulators, this is an exciting treatment regime that is clinically proven to be both safe and effective.

After your treatment, you may notice that the skin under your eyes appears slightly pink and lumpy for a short period. It’s important to note that, unlike treatments involving hyaluronic acid fillers, polynucleotides don’t create a filling effect. Therefore, any superficial lumps will dissipate entirely within a few hours following the procedure. This minimal impact allows you to continue with your daily routine without any significant interruption.

Bruising is rare, but should it occur, it can be easily concealed with a touch of makeup, ensuring you can maintain your usual appearance with little disruption.

While other standard polynucleotide therapies may require a course of 3-6 sessions, Dr Bong’s Polynucleotide EyeBright promises noticeable enhancement within a few days of your first treatment, with many patients opting for a second session for prolonged results.

Thanks to Dr Bong’s innovative formula that skilfully combines a high dose of polynucleotides with Botox, and the precision delivery using our state-of-the-art motorised device, many patients notice a softening of fine lines and wrinkles within just a few days post-treatment. However, the most significant results begin to emerge as your skin starts to produce new collagen and elastin. Typically, most patients see continuous improvements over the following 4-6 weeks.

It has been observed that patients who opt for two consecutive treatments, spaced 4-6 weeks apart, enjoy benefits that extend well beyond the initial 6 weeks, with results lasting up to 9-12 months.

While the high-dose polynucleotide injections lead to a permanent increase in collagen within the dermis, it’s important to remember that natural collagen production diminishes as we age. The enhanced collagen levels from our treatments are designed to counteract this natural decline. For sustained results, we recommend maintenance treatments every six months.

Most of our patients experience minimal to no side effects following the Polynucleotide EyeBright treatment. Any downtime is negligible, with some patients experiencing mild swelling and possibly slight bruising, both of which can be easily concealed with makeup.

Post-treatment, the skin under your eyes might appear slightly pink and lumpy for a few hours. Unlike treatments with hyaluronic acid fillers, polynucleotides do not produce a filling effect, so any superficial lumps typically resolve themselves swiftly, disappearing completely within a few hours. You should be able to carry on with your daily activities without disruption.

Our commitment is to achieve natural-looking results; thus, once any initial swelling or bruising subsides, the treatment remains completely undetectable, seamlessly blending with your natural aesthetic.

During your Polynucleotide EyeBright session at our clinic, you will be comfortably reclined while we meticulously navigate the injection handpiece across the under-eye area and into your crow’s feet. Throughout this precise process, we ensure your utmost comfort, keeping any discomfort to a minimum. Typically, just five injections per side are necessary.

The entire procedure is swift, lasting only 10-15 minutes. You may notice a gentle pressure and a mild tingling sensation as the handpiece touches your skin, but no anaesthetic cream is required. Dr Bong’s expert technique, combined with our advanced injection device, minimises discomfort—most of our patients report a pain level of just 1 to 2 out of 10.

After the treatment, you can immediately return to your daily activities, as there is no downtime. This level of comfort and efficiency not only reflects Dr Bong’s dedication to patient care but also sets our practice apart from others in the aesthetic field.

In other clinics, polynucleotides are often administered manually using a needle, which can compromise precision. To clarify, the outermost layer of our skin, the epidermis, consists of tough, flattened cells, while directly beneath lies the dermis, made up of softer, more active cells. Below the dermis is the subcutaneous tissue, primarily composed of fat.

Manual injections, though common, frequently miss the target layer— the dermis—instead depositing the polynucleotides into the subcutaneous tissue. While some benefits may still occur as the active ingredients diffuse back up into the dermis, optimal results are achieved through precise, consistent injection directly within the dermis.

Furthermore, manual techniques carry a greater risk of bruising and often lack the ability to dose accurately.

In stark contrast, the modern motorised injection device we employ at Essence Medical Cosmetic Clinic for our Polynucleotide EyeBright treatment enhances both accuracy and efficiency. This sophisticated technology not only minimises discomfort but also allows for the pre-setting of injection depths tailored to individual skin thickness. It ensures uniform distribution of polynucleotides AND Botox, delivering a precisely measured dose of 0.0033ml per injection through a cluster of nine microneedles simultaneously—a level of precision unattainable with manual methods. This approach ensures more uniform, harmonious results and a significantly enhanced treatment experience.

Once injected, the skin gradually absorbs polynucleotide DNA fragments, integrating seamlessly without forming lumps. Post-integration, they begin to influence skin function in three primary ways. Firstly, they activate and multiply fibroblast cells, enhancing their activity. This leads to improved cell renewal, increased new collagen and elastin production, and elevated hydration levels, which enhance the skin’s glow and resilience, improving elasticity and reducing the appearance of wrinkles.

Secondly, polynucleotides act as powerful antioxidants, scavenging free radicals that can cause cellular damage. Thirdly, they serve as agents that signal intensive skin repair, aiding in wound healing. This activity helps to refine skin texture, reduce discolouration, and even out skin tone. Additionally, polynucleotides slightly increase skin volume and tightening, contributing to an overall enhanced aesthetic effect.

The effectiveness of the treatment varies based on several factors. These include the initial condition of skin ageing, the skin’s inherent capacity to regenerate quality tissue when stimulated, and lifestyle factors. Together, these elements determine the ultimate outcome of the treatment.

Polynucleotides are long chains of DNA. Derived from salmon or trout, these highly purified DNA fragments are suspended in water to create an injectable solution. Brands of polynucleotides vary in their concentration of these purified substances. At Essence Medical, we have meticulously researched and selected brands with the highest concentration, tailored to meet the specific needs of our patients.

Dr Bong’s exclusive Polynucleotide EyeBright treatment combines a high dose of polynucleotides with Botox, delivered using a sophisticated motorised injection device. This innovative approach leverages the regenerative properties of both components to rejuvenate the under-eye area. The result is brighter, firmer, and more luminous skin, reflecting our commitment to using advanced treatments to enhance your natural beauty effectively.

Dermal fillers are primarily composed of a gel-like substance made from varying concentrations of hyaluronic acid. Their primary mechanism of action is through volumisation, creating a physical enhancement that is immediately visible, with further improvements developing over the subsequent 2-4 weeks. The effects of dermal fillers can last between 6 to 12 months, and often even longer. However, because hyaluronic acid attracts and retains water, it may not be suitable for areas prone to swelling or puffiness.

In contrast, polynucleotides work quite differently. They focus on stimulating cell regeneration, which means their effects take longer to become apparent as the skin undergoes natural renewal processes. Unlike fillers, polynucleotides do not provide a filling effect. When used in combination with other treatments, polynucleotides can contribute to a more comprehensive, holistic enhancement of the skin quality, addressing both structural and textural aspects for overall improved skin health and appearance.

Profhilo® is distinguished by its exceptionally high concentration of pure hyaluronic acid, which is celebrated for its ability to retain up to 1,000 times its weight in water. This remarkable hydrating capacity is what imparts a dewy, refreshed appearance to the skin following treatment.

Polynucleotides, on the other hand, do not contain hyaluronic acid. Their impact on the skin is more gradual, fostering improvement through a variety of bio-regenerative processes as previously described. This makes them an excellent choice for areas such as under the eyes, where Profhilo may not be the most suitable option.

Depending on your specific skin concerns, it is possible to combine both treatments to achieve enhanced, cumulative results. This integrated approach can be tailored to different aspects of skin health and aesthetics, maximizing the benefits of each treatment’s unique properties.

The short answer is – it depends. Polynucleotides, unlike tear trough fillers, do not provide volume and thus do not address the hollowness under the eyes. If your primary concern is the deflation or hollow appearance around the eye area, tear trough fillers may be a more suitable option.

However, it’s important to note that tear trough fillers are not particularly effective for softening fine lines and wrinkles, nor do they tighten the skin in the under-eye area. Polynucleotides excel in these areas by boosting the production of new collagen and elastin, which enhance the skin’s strength and smoothness, effectively reducing the appearance of fine lines and wrinkles.

Furthermore, the Polynucleotide EyeBright treatment offers benefits beyond those of traditional fillers. Unlike tear trough fillers, which simply act as a buffer, the high-dose polynucleotide injections actively repair and rejuvenate the skin, improving dark circles and pigmentation. Many of our patients have observed significant enhancements in the skin around their eyes after just one session of Polynucleotide EyeBright, making it a comprehensive treatment for overall eye area rejuvenation.

Skin boosters are composed of unlinked hyaluronic acid combined with amino acids, other hydrating agents, or antioxidants. They offer an instant, gentle lifting effect alongside hydration. The hyaluronic acid in skin boosters attracts water, leading to a mild plumping effect that can help diminish fine lines and enhance skin glow. However, these effects do not involve regeneration and are therefore short-term.

Polynucleotides, in contrast, provide a range of benefits. They stimulate fibroblast production of new collagen and elastin, initiate tissue repair, regulate pigmentation pathways, reduce inflammation, and enhance hydration. A key distinction is that polynucleotides do not volumise; they lack any filling effect and do not produce immediate results.

Unique among injectables, polynucleotides can influence skin function at a cellular level. When combined with other injectables, they offer a comprehensive stimulation that enhances the skin in a natural and effective manner. If your goal is to achieve subtle, long-lasting improvements, polynucleotides might be the ideal solution.

Polynucleotide injections are generally well-received and suitable for all skin types, including those with sensitive skin. However, since they are derived from fish DNA—specifically salmon or trout—they are not suitable for vegans.

Regarding individuals with fish allergies, opinions vary. Some experts suggest that the origin of polynucleotides from fish DNA might pose a risk to those with fish allergies. Others argue that due to the high level of purification these DNA fragments undergo, fish allergies should not necessarily preclude patients from receiving this treatment. Nonetheless, if you have a fish allergy, it’s crucial to discuss this with us before proceeding.

Additionally, polynucleotide treatments are not recommended for pregnant or breastfeeding women.

While there are no known long-term risks associated with the regular use of polynucleotides, and they may even be beneficial as part of a long-term skincare regime as we age, it’s important to consult with a specialist to determine if this treatment is appropriate for you based on your individual health profile and skincare goals.

Not at all! Dr Bong’s methodology is meticulously designed to ensure maximum patient comfort. Our cutting-edge injection device is equipped with some of the finest needles available globally, which, combined with Dr Bong’s refined injection technique, significantly minimises discomfort. Most patients report very little pain, typically rating their discomfort as only 1-2 on a scale of 10. This exceptional level of patient comfort not only highlights Dr Bong’s expertise but also sets his practice apart from others in the aesthetic field.

We accept cash or the following major credit and debit cards. We do not accept personal cheques.

If you are a new patient, a booking fee will be taken at the point of making your appointment.  Please read our full terms and conditions here.

We respect that your time is valuable, and we appreciate that you understand ours is too. Unfortunately, if appointments are cancelled or rescheduled at short notice, or if you do not attend an appointment, we cannot allocate your appointment slot to someone else; however, we still have overheads and staff salaries to pay. Please read our full terms and conditions here.

Please note for all patients, a £50 fee will be charged if you cancel or reschedule ANY appointment (including appointments which do not require an upfront deposit, such as a ‘check-up’ or review appointment) less than 48 hours before the appointment time. Patients who have pre-purchased a course of treatment will forfeit one of the treatments instead of paying this fee.

Late arrival to your appointment may result in reduced treatment time or the forfeiting of the appointment. We will endeavour to ensure that your appointment runs on time. However, for reasons beyond our control, we may need to cancel or postpone your appointment at short notice. In this unlikely event, we will try to contact you in advance. We do not offer compensation if we cancel or postpone your appointment.

Please read our full terms and conditions here.

If you are a new patient, a booking fee will be taken at the point of making your appointment.  Please read our full terms and conditions here.

As previously noted, we do not employ Lumi-Eyes, which contains only a minimal concentration (2mg) of polynucleotides per millilitre of syringe and is readily available online at a much lower cost. Our Polynucleotide EyeBright treatment features a bespoke formulation that contains ten times the concentration of polynucleotides per millilitre (20mg) compared to Lumi-Eyes, ensuring a superior and more potent treatment.

The following prices are indicative, and Dr Bong will provide a detailed breakdown of the total costs during your consultation:

– Starting at £425 per treatment.

– Starting at £750 for a course of two treatments, scheduled 4-6 weeks apart.

These prices reflect the advanced formulation administered with our state-of-the-art motorised injection device and the expert care provided during each session.